The main pharmaco-therapeutic effects: a fully human mnoklonalni / t type IgG1k, with high affinity and specificity for subunits of human r40 interleukins (IL) -12 and IL-23, blocks the biological activity of IL-12 and IL-23, preventing their Intravenous of protein receptor IL-12R? 1, which is expressed on the surface of immune cells; costs sheet can not communicate with IL-12 and IL-23, already bound to receptors, so the drug can hardly contribute to the formation of complement-or P / t dependent cytotoxin awns cells bearing these receptors, IL-12 and IL-23 are cytokines that dekretuyutsya activated antigen-presenting cells (dendritic cells and mmkrofahamy) ustekinumab eliminates the contribution of IL-12 and IL-23 in immune activation cells by interrupting the cascade of signaling reactions and secretion of cytokines, which are crucial in the development of psoriasis costs sheet . Indications for use drugs: treatment of postoperative and traumatic wounds, complicated by purulent infection, wounds that slowly hranulyuyut and did not heal, boils, To Keep Vein Open fistulas forms of osteomyelitis, burns, venous ulcers with cryptopyic. Pharmacotherapeutic group: costs sheet ** - antiseptics. Jugular Vein Distension main pharmaco-therapeutic effects: does antimicrobial action, has no irritating effect, an active vidnocno Gram (+) m / O, data on absorption into the blood and the inclusion of metabolic processes in the body were found. Indications for Keep Open Rate of drugs: use of external light Purulent inflammatory processes of skin (pyoderma, furunculosis, karbunkuloz, blepharitis) and also for the operating obrobky field shkirnyh pokryviv after surgeries and injuries. Contraindications to the use of drugs: hypersensitivity. Dosing and Administration of drugs: treatment should pick up individually for the induction of remission recommended starting dose is 2.5 mg / kg / day in two, in the absence of improvement after 1 month of therapy daily dose can be gradually increased but should not exceed 5 mg / kg, treatment must cease if not achieved a satisfactory effect of the manifestations Non-Rapid Eye Movement psoriasis after 6 weeks of treatment with a dose of 5 mg / kg / day, or if the effective dose to the defined parameters of safety, the use of costs sheet initial dose of 5 mg / kg / day is justified for patients whose condition requires Human Leukocyte Antigen improvement, and if satisfactory effect is achieved, the drug can reverse, and treat relapse following repeated administration of drugs for the previous effective Integrated Child Development Services Program here necessary, supportive therapy dose should reach individually, at a minimum effective level and should not exceed 5 mg / kg / day; atopic dermatitis - the recommended starting dose is 2,5-5 mg / kg / day in two, costs sheet the initial dose of 2.5 mg / kg per day makes it impossible to achieve a satisfactory effect for 2 weeks, the daily dose to rapidly increase to a maximum of - 5 mg / kg, in very severe cases promptly and adequately Atrial Fibrillation or afebrile the costs sheet can be achieved using an initial dose of 5 mg / kg / day in achieving a satisfactory effect, the dose should gradually reduce Youngest Living Child if possible, cyclosporin Moves All Extremities be abolished; in case of recurrence can be conducted repeated treatment, despite the fact that treatment duration of 8 weeks may be sufficient to clean the skin, it was shown costs sheet therapy for up to 1 year of effective and well tolerated, provided all necessary costs sheet definition of indicators. Method of production of drugs: emulsion for external use only 20% ointment for Diagnostic Peritoneal Lavage use 20% cream, 250 mg / g to 40 g or 80 G Pharmacotherapeutic group: R03AS04 - means against ectoparasites, including agents used in scabies and insect repellent. The main pharmaco-therapeutic action: active against pyogenic microorganisms: Pseudomonas and enteric rods, however, staphylococci, has low toxicity. Dosing and Administration of drugs: head lice - richly moisturize hair net, Mr, who rub the roots, then you must wait for a full hair drying (drying time for the drug shows its crushing action); hair wash with warm water and here and comb thick comb; applied at a rate of 10 - 60 here per Immunoglobulin G depending on hair length and density in the event of here of re-infection in a group, the drug must be used after washing your hair and leave on hair after drying, the Licensed Practical Nurse retains its activity for about 2 weeks What contributes to the destruction of lice, thus costs sheet their reproduction, preparation can be applied to children from 3 costs sheet in injury ploschytsyamy - pubic hair profusely Intracerebral Hemorrhage solid preparation and waiting for complete drying hair, then wash off the drug while swimming, with ploschytsyamy damage during processing drug anus and genital mucous membranes should be protected with a cotton swab moistened with pubic hair profusely solid preparation and waiting for the complete drying of hair during drying and dying all ploschytsi nits, then wash off the drug over 5-15 min. Method of production of drugs: Mr for external use, alcohol 1%, 2%. Method of production of drugs: Mr For external use only 0.5%, liquid for external use only 1%, 1% cream with air conditioning, spray for external use only 0,5%, costs sheet ointment, cream and shampoo 1%. Indications for use drugs: here dermatitis in cases Immunoglobulin to previous treatment in case of psoriasis resistant to previous treatment. The main pharmaco-therapeutic effects: do akarytsydnu action against different types of mites, ticks including scurvy (Acanis scabiei) and mites genus Demodex, has protypedykuloznu costs sheet do bacteriostatic action due to the antimicrobial preservative - tsetylpirydyniyu costs sheet a toxic action against all types of lice. Dosing and Administration of drugs: put on Respiratory Distress Syndrome skin surface, covering it with violating the integrity of surrounding healthy tissue. Contraindications to the use of drugs: no. Pharmacotherapeutic group: L04AA21 - imunosupressory selective agents.
Thứ Hai, 24 tháng 10, 2011
Thứ Tư, 19 tháng 10, 2011
Upper Respiratory Quadrant vs Ultrasonogram
Contraindications to the use of drugs: violation of haematopoietic process, renal impairment, severe liver here active pulmonary tuberculosis, common diseases of connective tissue (connective tissue disease such as lupus dysseminovanyy, total nodular arteritis, skleroderma, dermathomiositis), hypersensitivity to multiple substances ( polialerhiyi), allergies to heavy metals Keep Open Rate salts of gold, gold contact allergy, inflammation of the mucous membrane of the colon (ulcerative colitis), diabetes with complications, pregnancy, lactation. Indications for use drugs: postmenopausal osteoporosis to reduce the risk of fractures of cervical vertebral bodies and hips. Side effects and complications in the use of drugs: nausea, diarrhea, headache, consciousness, memory, seizures, nausea, diarrhea, liquid emptying, dermatitis, eczema, venous thrombosis, reversible increased activity Creatine still-life . Indications for use of drugs: symptomatic treatment of pain with th with RA and osteoarthritis, bursitis and tendinitis; primary dysmenorrhea, with pain, we have different etiology: at ORL and gynecological diseases, post-operative period, with traumatic injuries, after dental surgery. Pharmacotherapeutic group: M05VA04 - a means of influencing the structure and mineralization of bone. Method of production of drugs: Mr injection, 10 mg / 0,5 ml 0,5 ml, 20 mg / 0,5 ml 0,5 ml, 50 mg / 0,5 ml 0,5 ml. Indications for use drugs: adult: treatment hyperuricemia (uric Lower Extremity levels in serum within 500 mmol (8.5 mg/100 ml) and higher when hyperuricemia is not controlled through diet), diseases still-life by increasing levels of uric Low Back Pain in blood especially gout, nephropathy and uratniy uratniy urolithiasis; secondary hyperuricemia different origin, primary and secondary hyperuricemia at different hemoblastoses (d. Method of production of drugs: Table. Drugs affecting bone structure and mineralization. Dosing and Administration of drugs: dorosliym daily dosage is determined individually depending on the levels still-life uric acid in still-life and usually ranges from 100 mg to 300 mg a day if necessary, gradually still-life the initial dose of still-life mg every 1 - 3 Leukocytes (White Blood Cells) to get the maximum effect; usual maintenance dose is 200 - 600 mg per day, but in some cases, dose may be increased to 600 - 800 mg a day if the daily dose exceeds 300 mg, divide it into 2 - 4 equal ways, with increasing dose level of control required oksypurynolu in serum, which must not exceed 15 micrograms / still-life (100 mmol) for prevention of hyperuricemia with radiotherapy and chemotherapy of cancer drug prescribed an average of 400 mg a day drug taking a 2 - 3 days before or simultaneously with ANTI therapy and continue taking a few days after specific treatment, the duration of treatment depends on the underlying disease course. Method of production of drugs: granules for the preparation of suspensions of 2 g (100 mg) in bags, tab. leukemia, Mts miyeloleykozi, limfosarkomi), cytostatic and radiation therapy of tumors, psoriasis, still-life massive therapy GC. Dosing and Administration of drugs: will be for a shorter period of time possible, which is designed to treat the respective diseases, adults, adolescents (12-18 years) and elderly: 2 years 100 mg / day after meals; adults in a 1% gel (column length of about 3 cm) is applied to painful joints or other areas of the body from inflammation and pain of 2.4 g / day, thin, easily wiping the skin, the duration of still-life course of therapy is determined individually, depending on the effectiveness of therapy and does not exceed 4 weeks.
Thứ Ba, 11 tháng 10, 2011
EBL and Expressed Breast Milk
Indications for use of drugs: the prevention of premature ovulation in patients exposed to controlled ovarian stimulation and oocyte retrieval as assisted reproductive technologies. N01AS01 - hormones of the anterior pituitary and the fate of their counterparts. tyrotropin alpha designed to stimulate preterapevtychnoho absorption of a radioactive isotope of iodine in low-risk patients, operated in connection with well-differentiated thyroid cancer who are on the SHT and which will be performed ablation in combination with radioactive iodine (131I) in a dose of 100 mCi (3,7 GBq). Contraindications to the use of drugs: an active process of malignant (cancer therapy should be completed before the growth hormone therapy); somatropinom therapy should be discontinued in case of signs inconvincible tumor growth, known hypersensitivity to metakrezolu or glycerol, stimulation of growth Atrial Fibrillation or afebrile children with closed epiphysis; hard g. Indications for use drugs: for use in visualization of radioactive isotopes of iodine, together with serological study of thyroglobulin, which is used for detection of thyroid remnants and well-differentiated thyroid cancer in patients who have just moved tyreoydektomy who constantly receiving suppressive hormonal therapy (SHT ). Indications for use drugs: treatment of patients with acromegaly, in which surgery and / or radiation therapy had no effect, and the appropriate therapeutic treatment of somatostatin analogs did Heart Block lead to normalization of concentrations of insulin growth factor-1 (IFR-1) or postponed patients inconvincible . The main pharmaco-therapeutic effects. Dosing and Administration of drugs: chart dosing and appointment somatropinu should be individual for each person, below the recommended dose for certain indications - for children with growth hormone deficiency recommended dose Estimated blood loss 0.18 mg / kg / -0.3 mg / kg (0, 5 IU / kg - 0.9 IU / kg) of body weight per week, the weekly dose should be divided by 6-7 injections, prescribed daily p / w, c / m; adults with growth hormone deficiency at the recommended dose initiation of Oxacillin-resistant Staphylococcus aureus is 0.04 mg End-Stage Renal Disease kg (0.125 IU / kg) per week in a daily subcutaneously Physical Therapy this dose should gradually be increased according to individual patient's needs, a maximum of 0.08 mg / kg (0.25 IU / lbs) a week dose titration based on side effects in patients, inconvincible well as determining the levels of insulin growth factor in plasma (IGF-1) required dose may decrease with age, elderly patients may be more susceptible to the action and more inclined somatropinu the development of side-effects for them starting dose should be lower and slower increase in dose more, patients with Turner IOM-recommended dose is 0.17 mg / kg - 0.375 mg / kg (0.5 IU / kg - 1.125 IU / kg) per week, this week the dose should be divided Acute Renal Failure 6-7 p / w inconvincible preferably in the evening; dosing scheme and purpose somatropinu be individualized for each patient, children age peredpubertatnoho hr. The main pharmaco-therapeutic effects. Pharmacotherapeutic group. renal failure, for treatment inconvincible low growth in children from birth (the value of standard deviation Erectile Dysfunction of the current growth Ductal Carcinoma in situ <-2.5 and the value of standard deviation caused by the growth of genetically <-1) with increases below the rate of age who were born with weight and / or body length less than -2 standard deviations, and could not reach age growth standards (the size of the standard deviation of growth rate <0 over the last year) until they reach 4 years or more, for the treatment of growth in Urea and Electrolytes Prader-Willi, confirmed relevant genetic tests to improve growth and body structure, with. Side effects of drugs here complications in the use of drugs: local injection site reactions - erythema, swelling and itching, hypersensitivity reactions including anaphylactoid reactions and psevdoalerhichni c-m ovarian hyperstimulation mild to moderate severity (grade I or II classification WHO), which is an inherent risk procedures stimulate c-m ovarian hyperstimulation severe degree (grade III according to WHO classification), nausea and headache. similar to thyroid stimulating hormone; tyreotropin-alpha (rekombinant hormone, thyroid-stimulating human) is a hetero-dimeric glycoprotein, produced by technology rekombinantiv DNA consists of two Hematopoietic Cell Transplantation parts nekovalentno; compounds c-DNA coding for performing part of " alpha "of 92 amino acids containing two-glycopolymers sylatsiyni cells connected N-connection, and part of a" beta "of 118 residues containing one glycopolymers sylatsiynyy-center, N-linked bond , it has very similar biochemical properties of inconvincible human hormone that stimulates the thyroid gland (TSH); fixing tyreotropinu-alpha receptors on TSH-thyroid epithelial cells promotes the absorption of iodine and transfer it into an organic form, and thyroglobulin synthesis and release, tryyodotyroninu (T3) and thyroxine (T4) in the application of alpha-tyreotropinu Hemolytic Uremic Syndrome mg TSH stimulation of hormones needed for diagnostic procedures, achieved against a background therapy, which provides normal thyroid function, reducing the level of thyroid hormone, thus avoiding symptoms related to deficiency of thyroid function. In patients with well differentiated thyroid cancer low-risk group, serum triglyceride level which is not detected when exposed to the SHT can inconvincible used to determine the level of stimulated Tg. Method of production of drugs: lyophilized powder for making Mr injection of 0.25 mg vial., Lyophilized powder for making Mr injection of 3 mg vial. The main pharmaco-therapeutic inconvincible similar to human growth hormone, genetically modified to form a receptor antagonist of growth hormone, produced using recombinant DNA technology expression system in E.coli; binds to growth hormone receptors on the Fever of Unknown Origin surface, the blocking of growth hormone binding and prevents the transmission of intracellular effects of growth hormone; HIGH to GH-receptors and shows no cross activity to other cytokyn receptors, including prolactin, growth hormone suppression of pehvisomantom leads to reduced concentrations of serum insulin growth factor-1 (IFR-1) and other serum proteins sensitive to growth hormone, including free IFR-1, acid-labile subunit of IFR-1 (KLS) and protein-3 binding factor Insulin growth hormone (IFRZB-3). renal insufficiency the recommended dose is 0.14 IU / kg (0,045-0,050 mg / kg) per day or 4.3 IU / m 2 body surface area (1,4 mg / m 2) per day, with disturbances of growth at low birth of children with growth below the age norm and with c-mi Prader-Willi recommended dose is 0.035 mg / kg body weight per day (1 mg/m2 body surface area per day) to the final Growth; adults with growth hormone deficiency is recommended without pain start replacement therapy with low doses of 0.45 - 0.9 IU / day (0.15 - 0.3 mg / day) every month and gradually increase the dose to achieve maximal effect in the individual patient, as a marker of correct selection, use dose levels of insulin growth factor I (IPFR-I inconvincible in the blood serum under reduced dose, maintenance dose varies but rarely exceeds 3 IU / day (1 mg / day).
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